Analysis: Long -term load decreased 7 months after acute infection

Children under the age of 5 who were exposed to the uterus of the syphilis of maternal syphilis, including the people discovered at birth with innate syphilis, had a higher risk of hospital stays and, according to A, had longer hospital stays study carried out in Brazil and published yesterday in Jama Network Open.

Under the direction of London School of Hygiene and Tropical Medicine researchers, the study included data from the Center for Data and Knowledge Integration for the Health Birthdays of 8.3 million single births from January 2011 to December 2015 with a 3-year follow-up. Of all children, 30,039 syphilis were exposed to the mother, and 36,443 had innate syphilis.

The incidence of syphilis, a bacterial infection by caused by Treponema pallidumhas increased by more than 200% in countries with high incomes in countries with high incomes, as the researchers have stated.

“Syphilis can be sexually or vertically transferred from mother to child during pregnancy, which affects the developing fetus,” they wrote. “It is estimated that the mother’s syphilis has caused 350,000 adverse birth results worldwide, including dead birth, premature birth, low birth weight, deaths in newborns and innate infection.”

Congenital cases bear the 6 -fold of risk

During the study, 65.1% of children with innate syphilis and 31.3% with maternal syphilis were hospitalized at least once, compared to 19.0% in the non -exposed group.

These results indicate that close surveillance of exposed children is necessary and emphasize how important it is to prevent syphilis in women of childbearing age.

Compared to non-exposed children, those with innate syphilis had a 6-fold increased risk of the first hospital (Hazard Ratio (HR), 6.19), and those who were exposed to maternal syphilis were almost twice as high as the risk (Mr., 1.90). The highest risk of a hospital stay was found in the first month of life in congenital syphilis patients (HR, 11.53).

Although the risk decreased with increasing age, syphilis-exposed children had higher hospital stays than the non-exposed group up to the age of 36 months. Those who were exposed to syphilis in the uterus also had more and longer hospital stays.

“These results suggest the need for close monitoring of exposed children and emphasize how important it is to prevent syphilis in women of childbearing age,” wrote the authors of the study.